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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '369ede17cf3648eac731bc424624426f43e8e01e36f9b2df0b5e7e52cae27b81' 
  AND token = 'K4+ElzimdwXf000SRps5nE/JtgYy3p4se2CfmIxO8gE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}