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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8a65a61ca37cfd28f28a7f712b86565c0bc9ee0624d06510ca0285f32e10926' 
  AND token = 'Uoe/eaCheHEmHO0siMZFKwMCHFeVN0JL2YeT261fwFk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}