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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fcfe1bd3d9781100822bf607e1c9dc1558d8b1b73ba3b80383d2838839461f6' 
  AND token = 'NMWW0lW0fxYG3bgRLO8eOiUpLeGRb+dTZPqiTnq1VZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}