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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2389514e2e7d579b26e4037e41df83334ec92fb095207a0fbfefd6226143be4' 
  AND token = 'VI4f7tdTuIrB7K0LAaDosid5VvaNNNw1C9NWBTFQ6nc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}