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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5115b52a3227a613397372d37b2e3667720f0fd853fe7e9c5077440c9627b640' 
  AND token = 'XQinIy6xqLE+yPEYGMOht0LRxNOg7mbAH74HqXLUWh0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}