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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0565e843e6a44f0a669079f75cb7b51048e2899a87a3250e9afa0827fac9f049' 
  AND token = 'ZeGLxQrMbCaDE6ZNVWEBqGOyY+h5LL4bG8Il/hOVFQk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}