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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc46f7a08e4efd8c42266c4d5a9fa1d1dd0a4445a0c17cd570e24eda511932d9' 
  AND token = 'osIp5d1ge1OGqiXG+fYzcDYBO4i+gyrkqjXbS4uMjJg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}