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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46463c318dfcd30fa25dd931eff800a16460c6f2839b0fdb3f6990b35f3724a6' 
  AND token = 'iVxCfevGXSA6tvl0FBBTvoKeWfbFhIfOe3wl3eb54CU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}