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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3dc74447126e1aad4ade85c38ea584ddab36ada187d34c324b1d763dbdc69ed0' 
  AND token = '2W32e46WsIUNtGQPJx+28gDrb6bfdWPMS2Amo5Uc0y8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}