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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9101a517e0fc6a9c3f74858bf21e9480c68a1119bcc8be7ae93771303ad2991' 
  AND token = 'p5MV1QyKxWMhVHr80RyePibBp5Gm1nGv76CmFgawMiE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}