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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73ad4117b29b6d876edb81d52ce85efd02779f4d77ac7e3d042cc47f294aeb50' 
  AND token = 'cYZCaf466TNb8duAhqhwEi7WdfpsnMQpW5JcghCEfwA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}