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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8c449dd9941757c7fee2f9d0ab9891b1a24dc044f7c9081f411258542827eb5' 
  AND token = 'SPtm1v0c4WxuciETbiNiuuifcPvAu7l3YT7q7FDz0lI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}