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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c134fc9ab9b1f1bd3d3afefede8ce3a9cda5a5740c6c657cf47ec75023fd0f3' 
  AND token = 'CZq+L3aPwXk4q2NHaDeeTm9W8M1pjMH1RRgIqyFTeas=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}