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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c9d240150fd5f104ab90700440a2754d9d8387da602ab07cb959bd4766a85d0' 
  AND token = '8Ezx9yFakVJzBbghVDS4wKcOtVJL9VW6JMPzZ711JwI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}