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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4627c3eecfc2259f2b12f80c2127599f28b71614be94554793693210af2702a6' 
  AND token = 'S/SA4cKTsEalBEy3eZnw9UpM1/TtEnOOShn0fLvOc4g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}