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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ff006c74137830de76b780c287ffb35e0e20618adfe7fdc0f5e63500ff0ded2' 
  AND token = 'VXUOfkIPBPK1kDGHoRa+YEHJczE4QHuOqHV7OhUH9Ek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}