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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15b4924fd7f7c704c9a82a4a25edb8bfb0089547dff4884beb546f9ce725fde5' 
  AND token = '3e1w4ytMNKFK+nX8C+sE1CsGNPMlcd/4S7RQ/AbeBX0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}