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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '172e5e04642292dc01d682d74b02470dd001997c173e236171f8a13f38686717' 
  AND token = 'V7BRpCcKSIyND/lF3Vya9p+WDVIx/eV0FLHd8jf68oo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}