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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0fae3ebedcd6a0154942c9555f9978909f67cecbbe422b4edf286265b64e0c0' 
  AND token = 'MwXv0duHlFvCIfvXxFJ3wc+3sHSNfo+InQQ4q0wNZj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}