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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6ba7681f5161b342ced1846220fb0d54138a4a9d17c740b9ed686835569ed09' 
  AND token = '39qN8luTfthVPztMy6w41uuEaCS+kplVT86GbGytag4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}