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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fc7ff31af96ba0aaae9c1a4cbbb957ca63c45e36a63893f74eb08112b6b3146' 
  AND token = '1ISbx8KJ0QI6NI3sNDNn1EuuwiDvPKl0EAV99FpAMdk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}