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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6331f1820617669e899d7dea88202238b83429a1786a3b70d8f8ed74753da01c' 
  AND token = 'Gb4R9RBM1/8Pg0Xl6AFE++quk5gIQRhgIGUp74NNQrs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}