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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '761bb23d2b766197c9cb2e00bb7028e46cb90d7e14d39435fba01b166500cf08' 
  AND token = 'Ct1cWn5fSCxwhAmR1z4WUFj1BEokW6EIUO3EXmqXb1w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}