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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7467c33bcc6952a00a2ad1b30e000f24a2b2d7c86acecf50ad57a0acde6691d2' 
  AND token = 'gQi12OHNTjO4MRkkCfcn7/xrXuZ6A+HH+rfsezD/Wl4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}