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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0ce7f0d87b925e5e5132f849132f10e4ab5ec4b291f9a543cc873c9710e8194' 
  AND token = 'kTZj1XfMN170TXSGFK4pa8qq1rWYB45vLO7qiWiM2FU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}