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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '344e1916400e6d2554b4855eddbfa108bd2b2b3aae29709db3933c9f227a0e25' 
  AND token = '67GL9rSUIxngaEZ4QNd/CfAVzCsTyhggY0w6k3Q+j6U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}