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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1735681a7afb51d594f32be72049a7645a2db09bfc18b01f6559e346d1574df3' 
  AND token = 'ScdhOqMRz4whN4npDopg86FaEz4FhgaK2NbYvvZQOeE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}