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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8c709a6ea660372b951c2c2ae0b375c0aead697a43e41a4f3e940748220339e' 
  AND token = 'g9ko5SqyIxl+h6vE/fH6tO46rTUyHhGzaLk6XV9IO38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}