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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fd3d5687c28361e1455a7cf1be70e580539460ad586f3c0e3b9296d5adfad07' 
  AND token = 'QWrL2s87g5rsJW345KeHwmoWcN8hSyVNB6Otb74kvNI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}