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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '618df3fb7bd373a3f391bb3529d454039229aff009e5e579e59e8b5e77d3c1e7' 
  AND token = 'Ohfd+TY2OMySLhgDR7An/j2Hp8VTmrzneohCYL37ZiA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}