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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c498d422ccfa7a27dc9e358e855b1d5cb35cb139b1f70e8bc503e2006fee423' 
  AND token = 'snVRb3hpU8BZkUNU9Ch0I95C1lnTpuJ6yeEVUxnFZUY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}