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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e4ec83c187eb6cd706b26780fa88ea01fede36f068869da0b8558cc7ec4e748' 
  AND token = 'rlqzF+xlglygxogE6ipfJTcdQ7dwb8gRPqhYaGSU2mA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}