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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a5c5397b2486fc79293858a3e8f9f0262ff8219d936382dc0d9bd0f9eb24547' 
  AND token = 'uX8fPO+Mdmp+F9z/DX4g4MVz51XtRHfNcS66O/nzyqI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}