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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04ad0b4a346fbc9b7b921cd50ddf6977ab3f12e5395aee9fe4ca56cbd04c7350' 
  AND token = 'Pzyr5I1uIJSS4JZAtkDnsi+MjTTPrUOTrJAHNTRYiuc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}