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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ccf4d5e165a916252ad6182a6dd498c294ce6bf1d137d3b6ab7516fdcb27db29' 
  AND token = '1wdUo6LP7qeSvm/o1EE04uw+IdKlcvAeVzZ6k2Cb0BE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}