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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee8c619f8dd9070d8506eeef732509e628ba16bd0372f95d915828bade92dabc' 
  AND token = 'i22OdEd2OZW1MYLCcDxv/NACrbeDt6q9CZjbF8ZhHaQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}