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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f730ac866c4eb005fbbf4c0b205c860ffd2d1aede362ac5a441b620c46af8bc3' 
  AND token = 'cfy/curDCkWhLuCnMryfn+wpm9lepRfz80ZX1lgU9Mo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}