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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5b8a99a8d6d8cb4411e45d29a1090161fcaa197600a318c2eb920ff113f9aef' 
  AND token = 'nx5NGbHmwPYzQaqz4BDUGWV//KCRtetO4k57DoXTIaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}