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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4951ad838668434f8d272a42dc6f4cb8a4e16a8e305b63cd1c5442df3a88bbcc' 
  AND token = 'Owj0XqpeTXZ7zgOM+QnuyQ0iPiS0OGfXqYv0+b5Z0d8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}