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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4198b9068f47cdcd880bd17b7d1489574d3a3bbf3e1694055b8d7e9a3e4105c8' 
  AND token = 'YsoJ80llkOHsd22bDZecD6XSiLz25POhLgurwGIesHc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}