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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e031f027e54b422a5f3ebf078d33243be3a30c30e4d19e217c2f6766f5e7542' 
  AND token = 'pRpTEjZrmKUt27MhW22dIVloQlBvcDIe5s+Upll5F74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}