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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '687bf2af75a09f7a3b19c7eeaec59cd093dd5250d5261d97f4a18163cb9acc97' 
  AND token = '+gRFH3XlVolUisHY/87fvF0co3UdjGSh6OFL81qHVXY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}