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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ffa64e035ceb71b8600f8420eaa8c357a1d7661d3340cf4fd968939a753e8f5' 
  AND token = 'Scv3izWCn1SC9hNs8EfD1SsiD8TpyBfe9AJRR54dZ5o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}