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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b610465b47f9326f5547b7b839972bc4f31de5356d0d228d2d6ecd0c30ce3f9' 
  AND token = 'C9t/u21RHsUlbJ0+5Sc+KzYS5KMEa5tVKTDpHqGpRWI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}