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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e3ef77c5a314c6e93c102a386d774b989046d2d4cb52c83de330d509ac2cce0' 
  AND token = 'w6uTKHjW5BkEHSKoXP+wkJI8LstkgyOyppRLQORuAfg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}