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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c261168acd73b42a76a6329f6c4758576c9ffa4fa32258a8cbc405fdcae3783' 
  AND token = 'dnex8+BxQrqQc6ZXDCYtWjboFWlMs4TPznzBA2ELKMA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}