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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48c361570d8841d5a96b26fab30e8de8bb527586d6c9080130b80c0c5f36518c' 
  AND token = '+dzhgT85SOl3y2ZLVSwoAc++9w1BiYH8cpTqjpOY1+w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}