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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef1c9c3f871115d30454424b13c695a1ff29b907bf20324d48346d748cace491' 
  AND token = 'LCkE7N29SWrMY0X5k/6yf5MAvqrQSUD5ZYQrRmxhcbE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}