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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43d829078e739dd91f88cc65dc7a9df2a8e3cb666e1a334a06d7cd3b94cc7bc7' 
  AND token = 'Y/mfnrCp7Hq4aFNJM3HP6f2QhOKsv1PEXQJbudTneCQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}