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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fddf344fa34c1cbbf21c622da099868be90de6497dfc24a1b5cf3ce6a1f737fe' 
  AND token = 'fmhw4OtIAoEPFoh7FOfUAZH/5P16P/uniLIcxj2veWY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}